|本期目录/Table of Contents|

[1]徐晓津,李秀华,马一帆,等.50味中药与8种抗生素对变形假单胞菌的体外抑菌作用[J].集美大学学报(自然科学版),2019,24(6):409-418.
　XU Xiaojin,LI Xiuhua MA Yifan,LI Huiyao,et al.In vitro Bacteriostasis of 8 Kinds of Antibiotics 50 Kinds of Chinese Herbs and Their Compound Prescriptions on Pseudomonas plecoglossicida[J].Journal of Jimei University,2019,24(6):409-418.
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50味中药与8种抗生素对变形假单胞菌的体外抑菌作用(PDF)
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《集美大学学报（自然科学版）》[ISSN:1007-7405/CN:35-1186/N]

卷:
第24卷
期数:
2019年第6期
页码:
409-418
栏目:
水产、食品与生物工程
出版日期:
2019-11-28

文章信息/Info

Title:
In vitro Bacteriostasis of 8 Kinds of Antibiotics 50 Kinds of Chinese Herbs and Their Compound Prescriptions on Pseudomonas plecoglossicida
作者:
徐晓津1; 2; 李秀华3; 马一帆4; 李慧耀1; 2; 祁欣1; 2; 郑江1; 2; 鄢庆枇1; 2
(1.集美大学水产学院,福建 厦门 361021 ;2.福建天马科技股份集团有限公司,福建 福州 350308 ;3.厦门医学院附属第二医院中医科,福建 厦门 361021 ;4.厦门大学海洋与地球学院,福建 厦门 361005 )
Author(s):
XU Xiaojin 1; 2; LI Xiuhua 3MA Yifan4; LI Huiyao 1; 2; QI Xin1; 2; ZHENG Jiang1; 2; YAN Qingpi1; 2
(1.Fisheries College,Jimei University,Xiamen 361021,China2.Fujian Tianma Science and Technology Group Co.Ltd.,Fuzhou 350308,China 3.Department of Traditional Chinese MedicineThe Second Affiliated Hospital of Xiamen Medical College,Xiamen 361021,China;4.College of Ocean and Earth Sciences,Xiamen University,Xiamen 361005,China)
关键词:
变形假单胞菌; 中药; 抗生素; 抑菌作用
Keywords:
Pseudomonas plecoglossicida; Chinese herbs; antibiotic; antibacterial activity
分类号:
-
DOI:
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文献标志码:
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摘要:
用牛津杯法选择诃子、大黄、黄连等50种单方中药对变形假单胞菌、金黄色葡萄球菌进行体外抑菌试验，并选用抑菌作用较好的药物组成复方二联、三联中药，药物质量浓度为60，240 mg/mL。结果表明：单方中药中，诃子对变形假单胞菌抑菌作用明显，为极敏感；复方二联中药中，240 mg/mL的诃子+白芍等4种对变形假单胞菌的抑菌作用明显，为极敏感；复方三联中药中，60 mg/mL的黄连+板蓝根+黄柏等5种对变形假单胞菌的抑菌效果为极敏感，240 mg/mL的黄连+连翘+黄芪等6种对变形假单胞菌的抑菌作用为极敏感；变形假单胞菌对恩诺沙星、盐酸多西环素、硫酸新霉素及硫酸庆大霉素4种药物高度敏感。由此认为黄连+板蓝根+黄柏等11个复方三联中药与恩诺沙星对变形假单胞菌抑菌作用最强，同时筛选出多个抑菌作用效果良好的复方三联中药和抗生素，可用于鱼病防治研究。
Abstract:
Fifty kinds of Chinese herbs,which included Terminalia chebula,Rheum officinale,and Captis chinesis etc,were employed to test their antibacterial effect on Pseudomonas plecoglossicida and Staphylococcus aureus by using oxford -cup tests in vitro.Then the herbs that had optimal effect were chosen to compose as combination compounds prescription to compare their antibacterial activity.The concentrations of Chinese medicineswere 60 mg/mL and 240 mg/mL respectively.8 kinds of antibacterial drugs against Pseudomonas plecoglossicida were tested.Results showed that Terminalia chebula had obvious inhibitory effect.When the concentrations was 240 mg/mL,4 kinds of couplet compound prescriptions,such as Terminalia chebula and Paeoniatactilora pall,had obvious inhibitory effect.When the concentrations was 60 mg/mL,5 kinds of triple compound prescriptions,such as Coptischinensis,Radix isatidis and Cortex phellodendri had obvious inhibitory effect.When the concentrations was 240 mg/mL,6 kinds of triple compound prescriptions,such as Coptischinensis,Fructus forsthiae and Radix astragali had obvious inhibitory effect. Pseudomonas plecoglossicida were susceptible to enrofloxacin,oxytetracycline,neomycin sulfate and gentamicin sulfate.A part of Chinese drugs had no obvious inhibitory effect,11 kinds of triple compound prescriptions such as Coptischinensis,Radix isatidis and Cortex phellodendri had obvious inhibitory effects.The present study can provide traditional triple Chinese medicines formula and antibiotics for preventing the diseases of Pseudomonas plecoglossicida.

参考文献/References:

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更新日期/Last Update: 2020-01-01