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《集美大学学报（自然科学版）》[ISSN:1007-7405/CN:35-1186/N]

卷:

第18卷

期数:

2013年第6期

页码:

413-419

栏目:

水产科学与生物工程

出版日期:

2013-11-25

文章信息/Info

Title:

Recent Advances on Cathelicidin Antimicrobial Peptide from Fish

作者:

张东玲¹; 2; 关瑞章¹; 2

1.集美大学水产学院,福建 厦门 361021 ;2.鳗鲡现代产业技术教育部工程研究中心,福建 厦门 361021

Author(s):

ZHANG Dong-ling¹; 2; GUAN Rui-zhang¹; 2

1.Fisheries College,Jimei University,Xiamen 361021,China;2. Engineering Research Center of Modern Eel Industry Technology,Ministry of Education,Xiamen 361021, China

关键词:

Cathelicidin; 基因结构; 蛋白酶酶切; 表达机制; 生物活性

Keywords:

Cathelicidin; gene structures; proteolytic activation; gene expression mechanism;  biological activities

分类号:

-

DOI:

-

文献标志码:

-

摘要:

抗菌肽作为非特异性免疫因子，在机体抵抗病原感染中发挥重要的作用.Cathelicidin是目前发现的一个最大抗菌肽家族，具有多重生物学功能.鱼类Cathelicidin的研究虽比较滞后，但国内外学者已取得了一些研究成果.综述了前人鱼类Cathelicidin的研究成果，如基因结构、蛋白酶酶切作用、体内表达状况和生物学活性，以期为后续研究提供一定的研究基础和研究思路

Abstract:

Antimicrobial peptides are members of nonspecific immune factors that play essential roles in organism＇s immunity to pathogen.Cathelicidin is one of the major families of antimicrobial peptides that have multiple biological functions.Although the research on Cathelicidin in fish is less intensive than those in mammals,some significant progresses has been made recently.This article reviews some of these advances including new insights into gene structures,photolytic activation,gene expression mechanisms,and biological activities of Cathelicidin in fish.Finally,additional research questions and hypothesis are proposed for further investigation into fish Cathelicidin

参考文献/References:

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相似文献/References:

[1]刘岚萍,韩芳,张宇,等.大黄鱼Rac2基因的克隆及其抗病免疫作用分析[J].集美大学学报(自然科学版),2017,22(4):1.
　LIU Lanping,HAN Fang,ZHANG Yu,et al.Cloning and Analysis of Rac2 Gene in Disease-Resistant in the Large Yellow Croaker （Larimichthys crocea）[J].Journal of Jimei University,2017,22(6):1.

备注/Memo

备注/Memo:

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更新日期/Last Update: 2014-06-28