|本期目录/Table of Contents|

[1]胡文凯,张春晓,李学山,等.饲料中添加辅酶Q10对花鲈抗高温胁迫能力的影响[J].集美大学学报(自然科学版),2026,31(2):139-150.
　HU Wenkai,ZHANG Chunxiao,LI Xueshan,et al.The Influence of Dietary Coenzyme Q10 on the Resistance of Spotted Seabass (Lateolabrax maculatus) to Heat Stress[J].Journal of Jimei University,2026,31(2):139-150.
点击复制

饲料中添加辅酶Q10对花鲈抗高温胁迫能力的影响(PDF)
分享到：

《集美大学学报（自然科学版）》[ISSN:1007-7405/CN:35-1186/N]

卷:
第31卷
期数:
2026年第2期
页码:
139-150
栏目:
水产、食品与生物技术
出版日期:
2026-03-28

文章信息/Info

Title:
The Influence of Dietary Coenzyme Q10 on the Resistance of Spotted Seabass (Lateolabrax maculatus) to Heat Stress
作者:
胡文凯1; 2; 张春晓1; 2; 李学山1; 2; 王玲1; 2; 宋凯1; 2; 鲁康乐1; 2
（1.集美大学水产学院，福建 厦门 361021；2.厦门市饲料质量检测与安全评价重点实验室， 福建 厦门 361021）
Author(s):
HU Wenkai1; 2; ZHANG Chunxiao1; 2; LI Xueshan1; 2; WANG Ling1; 2; SONG Kai1; 2; LU Kangle1; 2
（1.Fisheries College,Jimei University,Xiamen 361021,China;2.Xiamen Key Laboratory for Feed Quality Testing and Safety Evaluation,Xiamen 361021,China）
关键词:
花鲈; 热应激; 辅酶Q10; 生长性能; 线粒体功能
Keywords:
Lateolabrax maculatus; heat stress; coenzyme Q10; growth performance; mitochondrial function
分类号:
-
DOI:
-
文献标志码:
A
摘要:
为开发提高花鲈（Lateolabrax maculatus）抗高温胁迫能力的功能性饲料，在基础饲料中分别添加0、10、20 mg/kg的辅酶Q10，分别记为Con、C10和C20。在水温为33 ℃的高温胁迫环境中，用这3种饲料分别投喂花鲈56 d。结果表明，在高温胁迫下，C10和C20都可显著提高花鲈的增重率（P＜0.05），并缓解花鲈鳃和肝脏组织结构损伤，减少肝脏脂肪沉积，显著提高花鲈总抗氧化能力（total antioxidant capacity，T-AOC）、超氧化物歧化酶（superoxide dismutase，SOD）和过氧化氢酶（catalase，CAT）的活性（P＜0.05），显著降低肝脏丙二醛（malondialdehyde，MDA）含量（P＜0.05），缓解氧化应激。进一步研究发现，C10和C20还能增强花鲈线粒体功能，显著提高柠檬酸合成酶（citrate synthase，CS）和琥珀酸脱氢酶（succinate dehydrogenase，SDH）的活性（P＜0.05），提高线粒体三羧酸循环速率，并显著上调线粒体自噬和生成相关基因pink1、mul1、atg5、pgc1α、pgc1β、nrf1的相对表达量（P＜0.05），促进线粒体的自我更新与修复，维持正常的线粒体功能。因此，在饲料中添加10或20 mg/kg辅酶Q10可以显著提高花鲈抗高温胁迫的能力。
Abstract:
To develop a functional feed that enhances the high-temperature stress resistance of Lateolabrax maculatus,this study focused on L.maculatus and added 0,10 and 20 mg/kg of coenzyme Q10 to the basic feed,denoted as Con,C10 and C20,respectively.In a high-temperature stress environment with a water temperature of 33 ℃,these three types of feed were fed to sea bass separately for 56 days.The results demonstrated that adding 10 or 20 mg/kg of coenzyme Q10 to the diet could significantly increase the lower weight gain of spotted seabass under heat stress,and alleviate the morphological damage of gill and liver of spotted seabass,reduce the fatty deposition of liver,significantly increase the activities of total antioxidant capacity (T-AOC),superoxide dismutase (SOD),and catalase (CAT) of spotted seabass,and significantly decrease the malondialdehyde (MDA) content in liver and alleviate oxidative stress.Further studies revealed that coenzyme Q10 also promoted the mitochondrial function of the spotted seabass,significantly increased the activities of citrate synthase (CS) and succinate dehydrogenase (SDH),increased the rate of the mitochondrial tricarboxylic acid cycle,and significantly up-regulated the relative expression of the mitochondrial autophagy and generation-related genes pink1,mul1,atg5,pgc1α,pgc1β and nrf1,which promoted the mitochondrial self-renewal and repair,and maintain normal mitochondrial function.So adding either 10 or 20 mg/kg of coenzyme Q10 to the diet could enhance the spotted seabass’s ability to withstand heat stress and significantly improve its growth performance.

参考文献/References:

相似文献/References:

[1]李磊,周文豪,蔡林森,等.油酸诱导花鲈肝细胞脂肪沉积模型的建立及二甲双胍对脂肪沉积的影响[J].集美大学学报(自然科学版),2020,25(1):1.
　LI Lei,ZHOU Wenhao,CAI Linsen,et al.Oleic Acid Inducing Hepatocyte Steatosis Model in Seabass (Lateolabrax japonicus) and Effect of Metformin on Fat Deposition[J].Journal of Jimei University,2020,25(2):1.
[2]姚成杰,刘佳珺,林振烔,等.红螯光壳螯虾Hsp70基因的特征及其在热应激下的表达[J].集美大学学报(自然科学版),2021,26(4):289.
　YAO Chengjie,LIU Jiajun,LIN Zhentong,et al.Characterization of Hsp70 Gene and Its Expression Under Heat Stress in Cherax quadricarinatus[J].Journal of Jimei University,2021,26(2):289.
[3]王秀琴,张春晓,鲁康乐,等.中草药对花鲈肝细胞氧化损伤的保护作用[J].集美大学学报(自然科学版),2021,26(5):408.
　WANG Xiuqin,ZHANG Chunxiao,LU Kangle,et al.Protective Effect of Chinese Herbal Medicine Oxidative Damaged Hepatocytes in Primary Culture of Spotted Seabass(Lateolabrax maculatus)[J].Journal of Jimei University,2021,26(2):408.

备注/Memo

备注/Memo:
更新日期/Last Update: 2026-04-21