|本期目录/Table of Contents|

[1]林茂,王雪虹,姚志贤.氟苯尼考在两种鳗鲡体内残留及消除规律的研究[J].集美大学学报(自然科学版),2011,16(2):92-96.
　LIN MaoWANG Xue-hongYAO Zhi-xian.Residue and Elimination of Florfenicol inEels Anguilla japonica and A.anguilla[J].Journal of Jimei University,2011,16(2):92-96.
点击复制

氟苯尼考在两种鳗鲡体内残留及消除规律的研究(PDF)
分享到：

《集美大学学报（自然科学版）》[ISSN:1007-7405/CN:35-1186/N]

卷:
第16卷
期数:
2011年第2期
页码:
92-96
栏目:
水产科学与生物工程
出版日期:
2011-03-25

文章信息/Info

Title:
Residue and Elimination of Florfenicol inEels Anguilla japonica and A.anguilla
作者:
林茂1; 2; 王雪虹1; 2; 姚志贤1
(1.集美大学水产学院,福建 厦门 361021;2.福建省高校水产科学技术与食品安全重点实验室,福建 厦门 361021)
Author(s):
LIN Mao1; 2WANG Xue-hong1; 2YAO Zhi-xian1
(1.Fisheries College,Jimei University,Xiamen 361021,China;2.Key Laboratory of Science and Technology for Aquaculture and Food Safety(Jimei University)Fujian Province,Xiamen 361021,China)
关键词:
氟苯尼考; 鳗鲡; 残留; 消除; 休药期
Keywords:
florfenicol; eel; residue; elimination; withdrawal time
分类号:
-
DOI:
-
文献标志码:
-
摘要:
研究了氟苯尼考在日本鳗鲡和欧洲鳗鲡体内的残留消除规律.在25 ℃下，以30 mg/kg的剂量多次口灌给药后1、2、3、5、8、12、20、30 d，取鳗鲡的血浆和肌肉、肝脏、肾脏等样品，加入内标氯霉素混合，经萃取过滤后采用反相高效液相色谱法检测，测定的平均回收率在97.8 %~101.3 %之间，日内变异系数为(3.23±0.49)%，日间变异系数为(4.08±0.85)%.氟苯尼考在鳗鲡体内消除较慢，在日本鳗鲡和欧洲鳗鲡血浆中的半衰期分别达7.8 d和8.3 d.氟苯尼考的最高残留限量，如规定为0.2 μg/g，则日本鳗鲡和欧洲鳗鲡用药后的最大休药期分别是38.7 d和28.5 d；如规定为1 μg/g，则最大休药期分别是19.0 d和11.2 d
Abstract:
In this paper,the elimination pattern of florfenicol in Japanese eel(Anguilla japonica) and European eel(A.anguilla)was studied.Some days after multiple daily gavage of florfenicol at 30 mg every 1 kg body weight,the plasma,muscle,liver and kidney samples of eels were collected, mixed with internal standard chloramphenicol,extracted and filtered,and then tested by reverse phase high performance liquid chromatography.The average recovery was from 97.8% to 101.3%.Inter-day variability was (3.23±0.49)% and intra-day variability was(4.08±0.85)%.Florfenicol was depleted so slowly in eel that half-life(t1/2) in plasma of Japanese eel and European eel came to 7.8d and 8.3d.In case maximum residue limit of florfenicol was 0.2 μg/g,the longest withdrawal time in Japanese eel and European eel following administration were 38.7 d and 28.5 d respectively.But if the limit was 1 μg/g,the time must be 19.0 d and 11.2 d respectively

参考文献/References:

-

相似文献/References:

[1]汪黎虹,关瑞章,李忠琴,等.10种单味中药对养殖鳗鲡主要致病菌的抑制作用[J].集美大学学报(自然科学版),2010,15(6):401.[doi:2010/12/30 0:00:00]
[2]汪黎虹,关瑞章,李忠琴,等.10种单味中药对养殖鳗鲡主要致病菌的抑制作用[J].集美大学学报(自然科学版),2010,15(6):401.
　WANG Li-hongGUAN Rui-zhangLI Zhong-qinLIU Hong-wei.The Inhibitation Effects of Ten Chinese Herbs on the Main Pathogenic Bacteria from Cultivated Eels[J].Journal of Jimei University,2010,15(2):401.
[3]郭松林,关瑞章,冯建军,等.基于16S rDNA序列和RFLP分析的病鳗分离菌株鉴定[J].集美大学学报(自然科学版),2012,17(2):81.
[4]王玉,关瑞章,黎中宝,等.鳗鲡病原性气单胞菌AFLP分型研究[J].集美大学学报(自然科学版),2012,17(4):253.
　WANG Yu,GUAN Rui-zhang,LI Zhong-bao,et al.DNA Fingerprint Typing Analysis by AFLP for Pathogenic Aeromonas sp.Isolated from Diseased Eels[J].Journal of Jimei University,2012,17(2):253.
[5]郭松林,王玉,冯建军,等.鳗鲡病原菌二联外膜蛋白基因工程表达载体的构建[J].集美大学学报(自然科学版),2014,19(5):330.
　GUO Song-lin,WANG Yu,FENG Jian-Jun,et al.Constrction of a Bivalent Expression Vector of Outer Membrane Protein of Two Pathogens Pathogenic to Eels[J].Journal of Jimei University,2014,19(2):330.
[6]李忠琴,关瑞章,郭松林,等.中药双联用复方对养殖鳗鲡主要致病菌的抑制作用研究[J].集美大学学报(自然科学版),2011,16(4):241.
　LI Zhong-qinGUAN Rui-zhangGUO Song-linWANG Li-hongLIU Hong-wei.Antibacterial Activity Analysis for Double-compounds of Chinese HerbsAgainst Pathogenic Bacteria from Cultured Eels[J].Journal of Jimei University,2011,16(2):241.
[7]牛达,吴佳睿,苏国成,等.3种抗生素在小白菜中的积累迁移及风险评估[J].集美大学学报(自然科学版),2022,27(2):114.
　NIU Da,WU Jiarui,SU Guocheng,et al.Accumulation and Migration Characteristics and Risk Assessment of Three Antibiotics in Pakchoi[J].Journal of Jimei University,2022,27(2):114.

备注/Memo

备注/Memo:
-
更新日期/Last Update: 2018-06-13