|本期目录/Table of Contents|

[1]翁朝红,谢仰杰,肖志群,等.中国鲎保守miRNA靶基因预测及功能分析[J].集美大学学报(自然科学版),2017,22(6):1-8.
　WENG Zhaohong,XIE Yangjie,XIAO Zhiqun,et al.Target Genes Prediction and Their Functional Analysis of Conserved miRNAs from Tachypleus tridentatus[J].Journal of Jimei University,2017,22(6):1-8.
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《集美大学学报（自然科学版）》[ISSN:1007-7405/CN:35-1186/N]

卷:
第22卷
期数:
2017年第6期
页码:
1-8
栏目:
水产、食品与生物工程
出版日期:
2017-11-28

文章信息/Info

Title:
Target Genes Prediction and Their Functional Analysis of Conserved miRNAs from Tachypleus tridentatus
作者:
翁朝红1; 2; 谢仰杰1; 2; 肖志群1; 2; 范赟颖1; 2
（1.集美大学水产学院，福建 厦门 361021；2.农业部东海海水健康养殖重点实验室，福建 厦门 361021)
Author(s):
WENG Zhaohong1; 2; XIE Yangjie1; 2; XIAO Zhiqun1; 2; FANG Yunying1; 2
(1．Fisheries College，Jimei University，Xiamen 361021，China; 2．Key Laboratory of Healthy Mariculture for the East China Sea，Ministry of Agriculture，Xiamen 361021，China)
关键词:
中国鲎; miRNA; 靶基因; GO功能注释
Keywords:
Tachypleus tridentatus; miRNA; target gene; gene ontology
分类号:
-
DOI:
-
文献标志码:
A
摘要:
以中国鲎、美洲鲎和果蝇EST为靶标，使用多个软件对中国鲎胚胎发育期高表达、高保守的19条miRNA进行靶基因预测。结果表明：8条miRNA在中国鲎EST中获得18条靶基因；17条miRNA在美洲鲎EST中获得616条靶基因；12条miRNA在果蝇EST中获得543条靶基因。这些保守miRNA潜在调控靶基因的功能，不但可能与血液凝集反应以及抗菌功能相关，而且还可能广泛参与生化调控、细胞组分组织架构、细胞组分空间定位、发育过程、多细胞器官构建、色素形成等生理过程。
Abstract:
In this paper,target genes of 19 highexpressed and conserved miRNAs from Tachypleus tridentatus embryos were predicted with ESTs from T.tridentatus,Limulus polyphemus and Drosophila melanogaster using several prediction softwares.18 target genes matched with 8 miRNAs were obtained from T.tridentatus ESTs,and 616 target genes matched with 17 miRNAs were obtained from L.polyphemus ESTs.Meanwhile,543 target genes matched with 12 miRNAs were obtained from D.melanogaster ESTs.The functions of these potential targets matched with the conserved miRNAs were not only potentially related to blood agglutination reaction and antibacterial function ,but also intensively participate in biochemical regulation,cellular component organization,establishment of localization,developmental process,multicellular organismal process,pigmentation and so on.

参考文献/References:

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2017-12-28